KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK9
All Species:
39.09
Human Site:
Y138
Identified Species:
57.33
UniProt:
P50750
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P50750
NP_001252.1
372
42778
Y138
Q
M
L
L
N
G
L
Y
Y
I
H
R
N
K
I
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001094502
352
40482
R122
N
G
L
Y
Y
I
H
R
N
K
I
L
H
R
D
Dog
Lupus familis
XP_548446
534
59045
Y300
Q
M
L
L
N
G
L
Y
Y
I
H
R
N
K
I
Cat
Felis silvestris
Mouse
Mus musculus
NP_570930
372
42743
Y138
Q
M
L
L
N
G
L
Y
Y
I
H
R
N
K
I
Rat
Rattus norvegicus
Q641Z4
372
42743
Y138
Q
M
L
L
N
G
L
Y
Y
I
H
R
N
K
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520593
314
36161
I99
M
K
A
A
N
V
L
I
T
R
D
G
V
L
K
Chicken
Gallus gallus
Q5ZKN1
372
42784
Y138
Q
M
L
L
N
G
L
Y
Y
I
H
R
N
K
I
Frog
Xenopus laevis
Q4V862
376
43205
Y142
Q
M
L
L
N
G
L
Y
Y
I
H
R
N
K
I
Zebra Danio
Brachydanio rerio
NP_997756
393
45129
Y159
Q
M
L
L
N
G
L
Y
Y
I
H
R
N
K
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477226
404
46768
Y170
Q
Q
L
L
N
G
L
Y
Y
I
H
S
N
K
I
Honey Bee
Apis mellifera
XP_396015
382
43973
Y144
Q
Q
L
L
N
G
L
Y
Y
I
H
S
N
K
I
Nematode Worm
Caenorhab. elegans
Q9TVL3
478
53575
N206
K
H
L
M
S
G
L
N
K
L
H
R
S
K
I
Sea Urchin
Strong. purpuratus
XP_798269
410
46418
Y167
K
Q
L
L
N
G
L
Y
Y
I
H
S
N
K
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LFT8
505
56711
H153
K
Q
L
L
T
G
L
H
Y
C
H
V
N
Q
V
Baker's Yeast
Sacchar. cerevisiae
P23293
657
74221
N184
L
Q
I
L
E
G
L
N
Y
I
H
C
A
K
F
Red Bread Mold
Neurospora crassa
Q871M9
545
61347
K146
L
Q
L
L
E
G
L
K
Y
L
H
A
N
H
I
Conservation
Percent
Protein Identity:
100
N.A.
92.4
68.5
N.A.
98.6
98.6
N.A.
77.9
93
89.3
85.5
N.A.
66
72.7
43.3
67.3
Protein Similarity:
100
N.A.
93.5
69.4
N.A.
99.7
99.7
N.A.
80.3
95.4
94.1
89.5
N.A.
75.9
83.2
56.4
75.8
P-Site Identity:
100
N.A.
6.6
100
N.A.
100
100
N.A.
13.3
100
100
100
N.A.
86.6
86.6
46.6
73.3
P-Site Similarity:
100
N.A.
20
100
N.A.
100
100
N.A.
13.3
100
100
100
N.A.
86.6
86.6
80
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
36
25.2
31.7
Protein Similarity:
N.A.
N.A.
N.A.
51
39.4
45.6
P-Site Identity:
N.A.
N.A.
N.A.
46.6
46.6
53.3
P-Site Similarity:
N.A.
N.A.
N.A.
73.3
53.3
60
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
7
0
0
0
0
0
0
0
7
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
7
0
7
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
7
% D
% Glu:
0
0
0
0
13
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% F
% Gly:
0
7
0
0
0
88
0
0
0
0
0
7
0
0
0
% G
% His:
0
7
0
0
0
0
7
7
0
0
88
0
7
7
0
% H
% Ile:
0
0
7
0
0
7
0
7
0
69
7
0
0
0
69
% I
% Lys:
19
7
0
0
0
0
0
7
7
7
0
0
0
75
7
% K
% Leu:
13
0
88
82
0
0
94
0
0
13
0
7
0
7
0
% L
% Met:
7
44
0
7
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
0
0
0
69
0
0
13
7
0
0
0
75
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
57
38
0
0
0
0
0
0
0
0
0
0
0
7
0
% Q
% Arg:
0
0
0
0
0
0
0
7
0
7
0
50
0
7
0
% R
% Ser:
0
0
0
0
7
0
0
0
0
0
0
19
7
0
0
% S
% Thr:
0
0
0
0
7
0
0
0
7
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
7
0
0
0
0
0
7
7
0
13
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
7
0
0
63
82
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _